On May 7, 2025, the American College of Rheumatology (ACR) released the full guideline for diagnosing, monitoring, and treating lupus nephritis (LN), which appeared in Arthritis & Rheumatology.

The finding might ... For patients with active lupus nephritis, obinutuzumab, a humanized type II anti-CD20 monoclonal antibody plus standard therapy is more efficacious for providing a complete ...

Background The therapy of lupus nephritis remains toxic and only partially effective but the benefits ... While the initial biopsy confirms the diagnosis, nephritis class and other parameters, ...

Introduction and purpose Lupus nephritis (LN) is a major cause of morbidity and mortality ... SLE group (non-nephritis), LN group (LN class I–V). The tissue slides were heated at 60°C for 60 min, then ...

Vera Therapeutics, Inc. (Nasdaq: VERA) today announced that on June 3, 2025, the Compensation Committee granted inducement awards consisting of non-qualified stock options to purchase 124,000 shares ...

cCentre for Epidemiology Versus Arthritis, The University of Manchester and NIHR Manchester Biomedical Research Centre, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health ...

Rapid reduction of glucocorticoid (GC) doses to 7.5 mg/day or less within 6 months may not worsen renal outcomes or increase relapse in patients with proliferative lupus nephritis (LN), recent study ...

The guideline recommendations advise universal use of hydroxychloroquine, minimizing steroids, and earlier introduction of ...

Belimumab, a monoclonal antibody, added to standard therapy may treat a broader range of patients with lupus nephritis than previously appreciated.

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Figure 1A (left): Kidney biopsy showing a normal glomerulus. Figure 1B (right): Kidney biopsy from a patient with class IV lupus nephritis showing a glomerulus with narrowing/closing of the ...

Renal disease is a major cause of mortality and morbidity in systemic lupus erythematosus. Among the histological classes of lupus nephritis ... change in histological class and determine residual ...