In this paradigm-changing study, researchers found that short fragments of circular DNA that encode cancer genes are far more common in cancer cells than previously believed. They showed that ...

Circular DNA, thought to be an accidental byproduct, is borrowing the cell’s DNA repair mechanisms to copy itself DURHAM, N.C. -- Like its viral cousins, a somewhat parasitic DNA sequence called a ...

But work in the past 10 years suggests those DNA tidbits, which are circular, aren’t just some cellular debris. Cancer cells use the circles to rapidly grab or shed genes linked to tumor growth ...

They exist as circular pieces of DNA in the nuclei of tumor cells outside chromosomes. Transcription of the amplified ecDNA genes can promote oncogenic processes, such as the increased expression ...

elegans, as well as in three human cell types. A 50-year-old lab technique is helping researchers better understand circular DNA, a lesser-known and poorly understood cousin of the linear version ...

can transform into cancer cells." "We were also able to show that certain types of circular DNA may accelerate neuroblastoma growth," explains Dr. Koche. "Testing for their presence may therefore ...

can transform into cancer cells." "We were also able to show that certain types of circular DNA may accelerate neuroblastoma growth," explains Dr. Koche and adds: "Testing for their presence may ...

Scientists have known about these ring-shaped sections of DNA for decades. Found inside our cells, they do not form part of our normal genetic information, which is stored in the form of chromosomes.

Extrachromosomal DNA (ecDNA) is a unique form of circular DNA that exists outside of normal chromosomes. Found exclusively in tumor cells, it often carries cancer-promoting genes (oncogenes ...

If you ask a biologist if humans have circular DNA, they are likely to say 'no.' That is because eukaryotic cell nuclei have linear chromosomes, while prokaryotes have circular nucleoids and plasmids.