Acute kidney injury (AKI) is a clinical syndrome characterized by a rapid and significant decrease in renal function that can arise from various etiologies, and is associated with high morbidity and ...

Epithelial cells line various surfaces of the body, including the skin, blood vessels, organs, and urinary tract. A raised amount of epithelial cells in a person’s urine may indicate an ...

PSTPIP2 reduced IL-19 secretion by inhibiting activation of the NF-κB pathway in renal tubular epithelial cells (RTECs), reducing the generation of neutrophil extracellular trap, which can participate ...

Salk Institute. (2023, November 28). Repairing nerve cells after injury and in chronic disease. ScienceDaily. Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2023 / 11 / 231128132322.htm ...

Luxa Biotechnology today announced the company will provide an update on the progress of a Phase 1/2a clinical trial evaluating transplantation of RPESC-RPE-4W to treat dry age-related macular ...

Among these damage-associated epithelial cell clusters, we found a damage-associated proximal tubular cell state (See DA-PT cluster), which shows reduced homeostatic gene expression (ex. Lrp2, Slc34a1 ...

Aristolochic acid (AA) induced nephropathy, a type of nephrotoxic CKD is characterised by cortical tubular injury, inflammation, leading to interstitial fibrosis. Extracellular vesicles derived from ...

We determined that H19 might serve as a facilitator in the process of CaOx nephrocalcinosis-induced oxidative stress and renal tubular epithelial cell injury, and we revealed that the interaction ...

Renal tubular injury in AAN, characterized by desquamation of necrotic tubular epithelial cells, loss of brush border, dilation of tubules, and formation of cellular casts, was semi-quantified by the ...

Acute kidney injury (AKI) results in the sudden loss of renal function primarily due to renal tubular injury. Repeated injury or maladaptive recovery lead to chronic kidney diseases. All forms of ...

Kidney disease is a worldwide health concern and currently there are no drugs to reverse kidney disease progression. Expanding evidence shows the potential of mesenchymal stromal cell (MSC)-based ...