Chromosome territories (CTs) with different gene ... of gene regulation requires much more detailed knowledge of gene expression in the context of nuclear architecture and organization.

Figure 1: Unique identification of 20 loci on chromosome (chr) 19 by RNA FISH targeting introns in human foreskin fibroblasts. By grouping actively transcribing genes into territories ...

Scientists identified 473 human genes that act as genetic “on/off switches,” shaping disease risk through tissue-specific or ...

Chromosomes occupy specific regions of the cell nucleus called chromosome territories. In somatic cells ... was not random and was directly related to the regulation of gene expression. “We have ...

Japanese researchers have successfully eliminated the extra chromosome responsible for Down syndrome using CRISPR gene ...

Subscribe for FREE Page and San Roman measured how X and Y chromosomes affected global gene expression by graphing how each gene’s expression changed in cells depending on the number of X or Y ...

a collaborative team of UCLA researchers have found that female mouse and human NK cells have an extra copy of an X chromosome-linked gene called UTX. UTX acts as an epigenetic regulator to boost ...

In your blood, colon, arteries, esophagus, fat tissue, age plays a much stronger role than your genetics in driving your gene expression patterns." Sudmant and colleagues also found that Medawar's ...

Copies of the same gene can appear on different chromosomes, boosting the survivability of humans as a species. Each gene is responsible for different functions. For example, some tell cells how ...

Suppressing chromosomal DNA repair ability increased the rate of duplicate chromosome elimination. The authors show that the chromosomal rescue reversibly restores both gene expression and ...