It has been known for several years that abnormal chromosome numbers lead to protein imbalances in the affected cells.

For decades, the Y chromosome — one of the two human sex chromosomes — has been notoriously challenging for the genomics community to sequence due to the complexity of its structure. Now, this elusive ...

The accurate distribution of chromosomes in an oocyte is essential for the correct transmission of genetic information to the ...

Changes in chromosome structure in any individual cell are probably of no importance. That one cell won't function well and might die soon. Translocations are important when they occur in a large ...

Superman syndrome, also known as 47, XYY, is a condition classified as a chromosomal aneuploidy (which is an abnormality in chromosome structure and/or number) in which males have an additional Y ...

These motors play distinct roles in manipulating chromosome structure. Swimming motors, similar to RNA polymerases—enzymes ...

Get Instant Summarized Text (Gist) A new AI tool accurately predicts the 3D structure of chromosomes in individual cells, overcoming challenges of noisy and incomplete single-cell data.

This research provides a deeper understanding of how motorized processes shape chromosome structures and influence cellular functions." Peter Wolynes, study co-author and the D.R. Bullard-Welch ...

Centromeres, specialized regions located at the center of chromosomes, are critical for ensuring proper cell division. During mitosis, centromeres serve as assembly sites for complex protein ...

The Y chromosome is unusually repetitive, making it particularly difficult to sequence and assemble; it contains a complex repeat structure that includes long palindromes, tandem repeats, and ...