Unexpected pregnancy loss can be a traumatic experience for fertile couples. The aim of the study was to assess the nature and type of chromosomal variants involved in early and late pregnancy loss ...

The discovery of two new genetic disorders comes from a study delivered through the National Institute for Health and Care ...

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Figure 1: The extent of linkage disequilibrium for the ARSACS region compared with the diastrophic dysplasia (DTD) region. Figure 6: Deduced amino acid sequence and structure of sacsin. The LD ...

97 Cells from individuals with Fanconi anaemia show increased chromosome breakage when exposed to DNA cross linking agents. At least 12 complementation groups have been defined and 11 genes identified ...

Microarray analysis identifies more chromosome abnormalities than traditional karyotyping in prenatal testing. Microarrays will also identify findings of unclear clinical significance that should ...

The presence of more than five chromosome abnormalities contributes to a decrease in survival, with an OS of less than 11 months versus 22 months in patients with ≤ 5 chromosome abnormalities. 12 The ...

Women age differently from men when it comes to health—particularly in conditions like cardiovascular disease and neurodegenerative disorders ... carry one X and one Y chromosome, women have ...