A pioneering research lab at the University of Illinois Urbana-Champaign has achieved another milestone using light-driven ...

Chiral bridged polycyclic structures ... molecular architecture found in many natural and biologically significant compounds. However, synthesizing these structures has posed substantial ...

Employing chiral organic bases allowed us to realize efficient desymmetrizations using carbon nucleophiles, such as 1,3-dicarbonyl compounds, cyanoacetates, and oxindoles. These reactions, performed ...

Centrosymmetric crystals have always absorbed equal amounts of left- and right-handed circularly polarized light—until now ...

More information: Liangliang Yang et al, Enantioselective type II intramolecular [5 + 2] cycloadditions of oxidopyrylium ylides using chiral-phosphoric-acid catalysis, Nature Synthesis (2025). DOI ...

HKUST chemists innovate in the synthesis of chiral bridged polycyclic compounds. Hong Kong University of Science and Technology. Journal Nature Synthesis DOI 10.1038/s44160-025-00803-w.

Remarkable progress in the enantioselective addition of Grignard reagents to carbonyl compounds has been made over the past decade. This enantioselective transformation now allows the use of these ...

A new platform for engineering chiral electron pathways offers potential fresh insights into a quantum phenomenon discovered ...

Asymmetric catalysis is a type of catalysis in which a chiral catalyst directs the formation of a chiral compound such that formation of one particular stereoisomer is favoured. Since the catalyst ...

Chiral solvating agent (CSA): A chiral compound that, when added to a racemic mixture, forms diastereomeric complexes with its enantiomers, leading to distinguishable NMR signals. Diastereomer ...