Mitochondria supply the body with the energy currency adenosine triphosphate (ATP), which drives all bodily activities. For ...

A new technique that alters protein production in mitochondria could help researchers understand mitochondrial diseases as ...

Astrazeneca AB has synthesized proteolysis targeting chimera (PROTAC) compounds comprising a protein cereblon (CRBN) binding moiety covalently linked to an estrogen receptor α (ER-α)-targeting moiety ...

ARV-102 is Arvinas’ investigational PROteolysis TArgeting Chimera (PROTAC) degrader targeting leucine-rich repeat kinase 2 (LRRK2), a multifunctional protein that has been implicated in ...