Characteristics of CNVs A change in copy number requires a change in chromosome structure, joining two formerly separated DNA sequences. These junctions give important insights into how the ...

The epigenetic state of chromatin, gene activity, and chromosomal positions are interrelated. A research team from the IPK ...

The last few years have provided us with a new level of understanding of how chromosomes are replicated, segregated and read - and how their 3D organisation influences expression of individual genes ...

This valuable paper describes the stiffness of meiotic chromosomes in both oocytes and spermatocytes. The authors identify differences in stiffness between meiosis I and II chromosomes, as well as an ...

The epigenetic state of chromatin, gene activity, and chromosomal positions are interrelated. A research team from the IPK Leibniz Institute (IPK) and the Karlsruhe Institute of Technology (KIT) ...

2007; Lim et al., 2008; Mestiri et al., 2010; Xiong et al., 2011; Chester et al., 2012; Zhang et al., 2013). Chromosome instability results in a high frequency of aneuploidy characterized by changes ...

Slizynska, H., and Slizynski, B. M., Proc. Roy. Soc. Edin., in the press. Slizynska, H., and Slizynski, B. M., Dros. Inform. Service, 16, 67 (1942).

Results prove that inversions can be generated in plants without causing further unwanted changes in the expression of genetic information.

Chromosomes are tightly coiled structures ... Scientists assign the letters A, T, C, and G to “bases,” which are part of the structure of DNA. Strings of these letters make up your complex ...

This commentary is a repost from "Sex on Wednesdays" by Martha Kempner on Substack. Find her other articles on The Queen...

In addition to these structural changes in genome organisation ... encodes a component of a protein structure called the synaptonemal complex, which connects chromosome pairs during the formation ...

and defects in chromosome structure (structural anomalies). These can be diagnosed by cytogenetic study (karyotype analysis) of virtually any tissue type. Numerical chromosomal abnormalities ...