Patients with type 2 diabetes mellitus are at a higher risk of developing heart failure compared with the healthy population. In recent landmark clinical trials, sodium-glucose co-transporter 2 (SGLT2 ...

Basal glucose transport in both soleus and extensor digitorum longus muscles in vitro was reduced by 73–88% in muscle-G4KO mice (Fig. 1d and e).Insulin-stimulated glucose transport was abolished ...

Increasing evidence has identified α-dicarbonyl compounds, the reactive intermediates generated during Maillard reaction, as the potential factors to cause protein glycation and the development of ...