The tumour suppressor FBW7 is the substrate recognition component of the SCF-type ubiquitin ligase that degrades several proto-oncogenes, including MYC and cyclin E. How do the numerous cancer ...

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Cell division is a process by which a cell, called the parent cell, divides into two or more cells, called daughter cells. Cell division is usually a small segment of a larger cell cycle.

Necrosis, an unprogrammed form of cell death, is identified as a key driver of aging and chronic diseases, particularly kidney disease, by triggering inflammation and tissue degeneration.