The emergence of multidrug-resistant bacteria poses a significant threat to public health. Particularly, they are becoming increasingly resistant to β-lactam antibiotics, which are one of the most ...

Klebsiella pneumoniae evolved ceftazidime-avibactam resistance during therapy via KPC mutations, prompting urgent reassessment of dosing and surveillance strategies in clinical settings.

Abstract. Background Ceftazidime-Avibactam (CAZ-AVI) plays a key role in the treatment of Multidrug Resistant Gram-Negative Bacilli (MDR-GNB) infections.In pediatrics, CAZ-AVI is clinically approved ...

Antibiotics are overused by some and out of reach for others - fuelling resistance and leaving deadly gaps in care.

However, more severe infections may need aggressive treatment using vancomycin or ceftazidime. A healthcare professional will evaluate a person’s eye infection to determine the best treatment ...

针对铜绿假单胞菌（Pseudomonas aeruginosa）日益严重的抗生素耐药性问题，研究人员通过果蝇（Drosophila melanogaster）感染模型，探究头孢他啶（ceftazidime）与维生素C联用的协同抗菌效果。研究发现，维生素C可使头孢他啶最低抑菌浓度（MIC）从12.5μM降至6.25μM，显著提高感染幼虫存活率（p<0.05），并通过 ...

Objective To investigate whether prophylactic nebulised antibiotic inhalation reduces the incidence of ventilator-associated pneumonia (VAP) in critically ill adults undergoing mechanical ventilation.

India is among the countries hardest hit by "antimicrobial resistance" It's a grim paradox, doctors say. On the one hand, antibiotics are being overused until they no longer work, driving ...