为解决免疫疗法（如免疫检查点抑制剂 ICIs）缺乏有效预后生物标志物的问题，研究人员开展了关于癌症干细胞标志物 CD44 在 33 种人类癌症中预后价值及免疫功能的研究。结果发现 CD44 与肿瘤分期、预后及免疫微环境相关，可作为潜在免疫治疗靶点和生物标志物。

Dr. Claire Trivin-Avillach: The diagnostic tests in this case were a serum enzyme-linked immunosorbent assay (ELISA) and indirect immunofluorescence testing for circulating anti-PLA2R antibodies.

Bone tumor organoids are three-dimensional cell culture models derived from patient tissues or cells, capable of highly replicating the growth patterns and cell interactions of bone tumors in vitro.

Immunofluorescence: The pathognomonic feature is predominant or codominant IgA deposits in the mesangium. These deposits are typically granular and may be accompanied by C3, IgG, and/or IgM.

Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, College of Pharmaceutical Sciences, Zhejiang University of Technology, China; Department of Molecular, Cellular, ...

State Key Laboratory of Vaccines for Infectious Diseases, Center for Molecular Imaging and Translational Medicine, Xiang’An Biomedicine Laboratory, School of Public Health, Xiamen University, Xiamen ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Rheumatoid arthritis (RA) is associated with ...

另一方面，精氨酸（R）、甘氨酸（G）和天冬氨酸（D）（RGD）等结合域，或球状 N 端连接结构，是 EVs 膜上受体与 ECM 成分（如 α 4 β 1 整合素和 CD44）结合的关键因素。 鉴于 EVs 与 ECM 相互作用的重要性，本文着重回顾了有关 EV 表面生物分子的研究进展，旨在 ...

This article has been updated with information from Leesburg Police Department spokeswoman Michele Bowman. At his April 3 sentencing in Loudoun Circuit Court, Zeon Detwan Garner apologized for ...

Next-generation sequencing has enabled precision therapeutic approaches that have improved the lives of children with rare diseases. Congenital diarrhea and enteropathies (CODEs) are associated ...