Transforming growth factor (TGF)-α is neurotrophic for midbrain dopaminergic neurons in vitro. Here I investigated whether a null mutation in the TGF-α gene affects the normal development or ...

The novel cue-induced analgesia paradigm allowed a compelling identification of a brainstem circuit element, i.e., somatostatin-expressing neurons within the ventrolateral periaqueductal grey that ...

This research also has potential implications for Parkinson’s, which is known to be caused by the death of midbrain dopamine neurons, specifically in substantia nigra pars compacta. The type of cells ...

Late-night scrolling isn’t the only thing sabotaging your slumber. New research suggests that a common daily habit may send your brain into overdrive while you sleep — even if you do it hours ...

Serotonin transporter (SERT) terminates serotonin signaling in the brain by enabling rapid clearance of the neurotransmitter. SERT dysfunction has been associated with a variety of psychiatric ...

A new study has found that depression is linked to an increased risk of dementia in both mid and later life. The new research, which is published in eClinicalMedicine, was led by Jacob Brain and ...

A study published in Neuron last week, conducted at UCL's Wellcome Trust Centre for Neuroimaging, shows that the conventional view of how our brains learn has to be revisited. Previously, it was ...