More information: Paula Ortiz-Sánchez et al, Loss of SRSF3 in Cardiomyocytes Leads to Decapping of Contraction-Related mRNAs and Severe Systolic Dysfunction, Circulation Research (2019).

Representative compounds were added to cardiomyocytes in a 1:3 dilution series to determine IC50 values. As before, cardiomyocyte contractions were visualized using the EarlyTox Cardiotoxicity dye ...

Researchers have now delineated how specific ion channels in the membranes of cardiomyocytes ensure that the heart beats in and on time. Electrical signals regulate the rhythmic contractions of ...

How the cardiomyocytes that we start developing ... important structures that help to coordinate sarcomere contraction. These too were greatly disrupted in the mutant myocytes.

But in the adult heart, "cardiomyocytes barely divide ... severely impairing heart contraction. To investigate the mechanism through which SRSF3 supports heart contraction, the team compared ...

Cardiomyocytes, or cardiac muscle cells are the main type of heart cells and act as the motor unit to drive heart contraction and relaxation. Particularly, adult human primary cardiomyocyte is a ...

"The intracellular effects of focused near-infrared femtosecond laser irradiation are shown to cause contraction in cultured neonatal rat cardiomyocytes. By periodic exposure to femtosecond laser ...

But in the adult heart, "cardiomyocytes barely divide ... severely impairing heart contraction. To investigate the mechanism through which SRSF3 supports heart contraction, the team compared ...