Because the high-energy phosphate storage within the cardiomyocyte is minimal, only sufficient to sustain the heart beat for a few seconds, a tight coupling of ATP production and myocardial ...

An international team of researchers has uncovered a groundbreaking discovery in the fight against heart disease. They found ...

‡ Department of Chemistry, the James Franck Institute and the Institute for Biophysical Dynamics, The University of Chicago, Chicago, Illinois 60637, United States Article Views are the ...

Researchers have discovered how cholesterol can disrupt the internal functioning of the heart by accumulating in the ...

After 14 days of CCB treatment, cardiomyocytes in general demonstrated weaker contraction and relaxation, with verapamil exhibiting the greatest inhibition (Figure 1B; Online Figure VI). CCB-treated ...

SarcAsM (Sarcomere Analysis Multitool) is an AI-powered Python package for cardiomyocyte sarcomere analysis. It enables precise multilevel structural and functional assessment of sarcomeres in ...

Department of Endocrinology and Metabolism, second Affiliated Hospital of Nanchang University, Nanchang, People’s Republic of China, The second Clinical Medical College, Nanchang University, Nanchang ...

To their surprise, heart muscle cells called cardiomyocytes emerged as the dominant initiators of borderzone IFN signaling. They found that mechanically stressed cardiomyocytes in the borderzone ...