The defects in molecular and cellular processes that constitute the triggers of specific pathologies are referred to as mechanisms of disease. Research in this area is vital for designing ...

Mechanism of action describes the process by which a molecule, such as a drug, functions to produce a pharmacological effect. A drug’s mechanism of action may refer to its effects on a ...

Sometimes the response to the initial treatment may indicate the mechanism underlying the condition. If the patient's thyroid hormone levels fall within a week or two, this indicates that high-dose ...

Amazon’s Pricing Mechanism Could Breach Competition Law, German Regulator Says The preliminary assessment is the latest salvo from a European regulator against a U.S. giant By ...

Mechanism has teased its first Switch 2 accessory coming this summer. The company, which made its name with the Deckmate accessory ecosystem for Steam Deck and other handhelds, has unveiled the ...

During embryonic development, thousands of cells divide and move as one. Understanding the mechanisms that coordinate this collective behavior remains a significant challenge in biology and the ...

The effect of inorganic salts and ionic liquids (ILs) on the solution properties of scleroglucan (SG), an increasingly used and researched natural biopolymer, is reported here. Various rheological, ...

Get Instant Summarized Text (Gist) Sleep disorders and hearing loss are linked by shared biological mechanisms. Different sleep stages affect auditory perception, and hearing loss can disrupt ...

India has called for action to curb non-tariff barriers, address trade distortions caused by non-market economies, and restore a strong dispute settlement mechanism at the WTO, Commerce and ...

Methods and analysis The trial aims to establish whether the combination of a single dose of rituximab (500 mg) and a 12-month course of antithyroid drug (usually carbimazole) can result in a ...

Background: Neoadjuvant dual HER2 blockade + chemotherapy (NAC) is standard of care for early-stage HER2+ breast cancer (BC), leading to pathological complete response (pCR) associated with high cure ...

For context, OpenAI's Codex Mini, o3, and o4-mini models managed to bypass the shutdown commands and mechanisms. Codex sabotaged the mechanism 12 times, while o3 bypassed the shutdown command 7 times.