Calcium-activated proteolysis by calpain is a candidate to participate in this form of pathology because it is activated under ischemic conditions and its activation results in the degradation of ...

A major problem in people with Parkinson’s disease is calpain, a protein that is highly expressed in their brains and known for being the cause for neuronal degeneration. Even though E2 has been known ...

A new role of calcium in the development of muscles has been reported by two RIKEN biologists. Stress is generally damaging and destructive, but it can sometimes spur productivity and creation.

[1]. Liu C,et al. Characterization of ionomycin as a calcium ionophore. J Biol Chem. 1978 Sep 10;253(17):5892-4. [2]. Chatila T, et al. Mechanisms of T cell activation by the calcium ionophore ...

骨钙素（OC）是一种仅在骨组织中发现的49个氨基酸的肽，在物种之间高度保守。它是一种维生素K和D依赖性蛋白，由成骨细胞、骨细胞和成牙本质细胞产生。它沉积在细胞外骨基质中，存在于血清中。血清骨钙素在肾脏和肝脏中水解，被认为是成骨细胞活性和骨 ...

After 2 months of treatment with high dose LBE, calpain-2, calpain-5, and the oxidative RNA marker 8-OHG were downregulated, and presynaptic densities in the inner plexiform layer but not the outer ...