Here, we show that pharmacologic activation of the ISR kinases HRI or GCN2 promotes adaptive mitochondrial elongation and prevents mitochondrial fragmentation induced by the calcium ionophore ...

A zero calcium score with high cholesterol may mean a person is at a lower risk of coronary heart disease. It means imaging does not show a buildup of calcified plaque in the heart’s blood vessels.

Department of Medical Chemistry, Faculty of Chemistry, Adam Mickiewicz University, Uniwersytetu Poznańskiego 8, 61−614 Poznań, Poland ...

Consuming the amount of calcium found in a glass of milk could reduce the risk of colorectal cancer, according to a new study involving women. That was regardless of whether the calcium came from ...

IT is recognized that the various influences, nervous and osmotic, which bring about release of the hormones vasopressin and oxytocin from the neuroseeretory terminals in the posterior lobe of the ...

The findings of this valuable manuscript advance our understanding of the significance of Bestrophin isoform 4 (BEST4) in suppressing colorectal cancer (CRC) progression. The authors used appropriate ...

According to this summary in Science Direct, ionophores kill coccidia protozoa at a specific stage of growth by interrupting movement of ions through the cell membrane and changing the equilibrium of ...

2014) and in conditional knock-out mouse (Simon et al., 2004). Cellular calcium homeostasis is intimately dependent on functional mitochondria. Therefore, frataxin overexpression in 3T3-L1 adipocytes ...