PCR and Sanger sequencing methods are used for gene polymorphism analysis because they produce chromatograms with target amplicon base lengths and several SNPs that can be analyzed ...

Climate Solutions A gene could be key to growing rice, and feeding billions, in a hotter world. Researchers say they can improve rice harvests and grain quality by essentially turning off a ...

In February, KJ got his first IV infusion with the gene editing therapy, delivered through tiny fatty droplets called lipid nanoparticles that are taken up by liver cells. While the room was abuzz ...

In the 3’ untranslated region of the CYP2B6 gene, there is a SNP, rs707265 G allele, the change creating miR- 1623/4269 and 3622a 5p binding sites, absent in the A allele suggesting a role for miRNA ...

For sertraline and CYP2C19 or CYP2B6 pairs, the incidence was 11.0% (n = 352). Among all antidepressants, paroxetine had the highest incidence of actionable drug-gene interactions related to CYP2D6 at ...

Gene was married to his first wife from 1956 to 1986. Gene told the South Florida Sun-Sentinel in 1985 that he didn’t “leave” Faye for Betsy. “By the way, I did not leave my real-life wife ...

Pfizer got Beqvez in 2014 from Spark Therapeutics. The gene therapy biotech was later acquired by Roche, which has had its own struggles with the modality in hemophilia.. With its Sangamo ...

Manipulating Gene Expression to Treat Disease. Several of our scientists study gene regulation in specific cancers, including cancers of the blood, lung, pancreas and prostate. They seek treatment ...

After a major spike during the COVID-19 pandemic years, cell and gene therapy investment has since slowed down considerably. The figures now look pale in comparison to the $19.9 billion made in 2020 ...

Purpose: To investigate the effects of hepatic enzyme activity variations and CYP2B6 gene polymorphisms on the in vivo and in vitro metabolism of efavirenz. Main methods: In vitro enzyme systems using ...