Cell line development plays a pivotal role in the manufacturing of therapeutic proteins, vaccines and other biologics.

Gene therapies to treat rheumatoid arthritis have evolved slowly, but one is ready to move into human trials and an ...

CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...

Potent in vivo gene editing in skeletal muscle of non-human primates by a novel, ultracompact CRISPR system delivered via a single AAV vector.

NanoCas, an ultracompact nuclease, enables efficient muscle editing in NHPs using a single AAV - advancing gene editing for hard-to-target tissues.

Kennedy Jr. will di­vest his in­ter­ests in sev­er­al bio­phar­ma com­pa­nies, in­clud­ing CRISPR Ther­a­peu­tics and Drag­on­fly Ther­a­peu­tics, if con­firmed by the ...

This important study offers insights into the function and connectivity patterns of a relatively unknown afferent input from the endopiriform to the CA1 subfield of the ventral hippocampus, suggesting ...

The T cells are activated with cytokines to stimulate cell division, and a viral vector is then used to engineer the cells to express a chimeric ... with promising results from gene-editing ...

It's clear though that these companies need time. Even with the only approved CAS9 based treatment out there, CRISPR is still years away from achieving its potential. In a recent update to ...

CRISPR-Cas9 is one of the biggest discoveries of the 21st century. Since it was developed in 2012, this gene-editing tool has revolutionized biology research, making it easier to study disease and ...

Not long after the development of CRISPR-Cas9 gene editing in 2013 ... Building on previous work by the vector-engineering lab of Ben Deverman at the Broad, the team developed a pair of adeno ...