Introduction: During T cell development, heterogeneous nuclear ribonucleoprotein (hnRNP) L is known to regulate CD4 T helper subset differentiation ... For intracellular staining of transcription ...

T cells are a type of white blood cell that is central to your immune defense. Four types that serve different functions include: CD4 and CD8 are two different types of glycoprotein found on the ...

Taken together, these data show that the immune microenvironment of post-Y90-RE tumours was infiltrated by multiple activated immune subsets and was less immunosuppressive compared with the T REG ...

为探究宿主效应 CD4 + T 细胞能否被过继转移的 CD8 + T 细胞激活，研究人员开展了相关研究。结果发现小鼠肿瘤特异性 Tc9 细胞可招募并激活宿主效应 CD4 + T 细胞控制抗原缺失复发肿瘤。该研究揭示了体内激活肿瘤特异性 CD4 + T 细胞的机制。 宿主效应 CD4 + T 细胞是 ...

Tet1/3 supported chromatin accessibility at TCR-responsive regulatory elements enriched in motifs belonging to bZIP, ETS, RUNT, and NFAT transcription factor families, which are known transcriptional ...

Subcutaneous LCMV infection induces T H 1 cell polarization while largely compromising T FH cell differentiation and humoral immunity. T-cell-derived IFN-γ produced in the first days upon infection ...

She hasn't heard from him since ... known for his swift moves as a Bath winger and his stint on The X Factor: Celebrity in 2019 with Try Star mates Thom Evans and Ben Foden, was last captured ...

本期推荐：研究团队通过小鼠模型和人胎儿脑组织实验，揭示CD4 + T细胞通过分泌IFN-γ抑制神经元中巨细胞病毒（CMV）的复制和再激活，为先天性CMV感染导致的神经发育障碍提供治疗新靶点，成果发表于《Journal of Neuroinflammation》。 在人类疱疹病毒家族中 ...

Previous clinical studies have indicated reduced circulating mucosal-associated invariant T (MAIT) cells in individuals with coronary artery disease. However, the precise role and underlying ...

This important study utilizes humanized mice, in which human immune cells are introduced into immune-deficient mice, to provide convincing evidence that two helper CD4 T-cell subsets, T-follicular ...