Objective The present study aimed to provide a comprehensive evaluation of the postmarketing safety of belimumab based on the Food and Drug Administration Adverse Event Reporting System (FAERS) ...
Preclinical studies using transgenic mice expressing human CD19 have shown that pre-B cells and their malignant counterparts, as well as pre-existing antibody-producing and autoantibody-producing ...
Institute for Advanced Optics, Hunan Institute of Science and Technology, Yueyang, Hunan 414006, China School of Information Science & Technology, Hunan Institute of Science and Technology, Yueyang, ...
This case of a successful treatment of multi-refractory primary immune thrombocytopenia adds to the growing body of evidence supporting the use of CD19 CAR T-cell therapy in B cell-driven autoimmune ...
Belimumab is under clinical development by GSK and currently in Phase III for Interstitial Lung Diseases (Diffuse Parenchymal Lung Disease). According to GlobalData, Phase III drugs for Interstitial ...
CD19, a B-cell surface protein, is expressed across B-cell development and it is expressed on almost all B-cell malignancies, such as ALL, chronic lymphocytic leukemia (CLL) and several non ...