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RESUMO . Racional: CD133 e AXL são descritos na literatura como marcadores de células-tronco tumorais, e c-MYC cumpre papel chave como mecanismo de regulação celular no câncer colorretal (CCR).
Researchers found that clinically achievable doses of curcumin, the active compound in turmeric, target and suppress ...
这项研究将全人源抗cd133抗体(rw03)与螯合剂dota-nhs巧妙结合,再装载放射性核素镥-177,打造出兼具靶向性与杀伤力的治疗武器。 体外实验显示,这个放射性免疫复合物与HT-29结肠癌细胞结合时表现出惊人精度,亲和力达0.30±0.03 nM水平,超过75%的抗体保持活性状态。
为探究 cd133 在甲状腺乳头状癌(ptc)预后中的作用,爱荷华大学医院和诊所等机构研究人员开展了相关研究。结果显示,cd133 表达与 ptc 患者无复发生存(rfs)的关系在男女间存在差异,这为 ptc 复发风险分层提供了新依据。
cd133(也称为prom1)是一种细胞表面糖蛋白,广泛应用于干细胞和癌症研究。作为常用的表面标记物,它被用于识别具有干细胞 ...
CD133 is a transmembrane protein that is expressed at low levels in normal tissue but is overexpressed by a variety of tumors, including SCLC. We previously explored CD133 as a biomarker for a novel ...
CD133 expression in undifferentiated cells has been utilised to identify, isolate and enrich stem cells [19,21] and neural progenitor from the developing and adult brain.
CD133 + Exo treatment of T2DM-stroke mice significantly decreased liver steatosis, hepatocellular ballooning, fibrosis, serum ALT activity, and NAS compared to T2DM-stroke mice at 28 days after stroke ...
CD133 as a biomarker for an autoantibody-to-ImmunoPET paradigm for the early detection of small cell lung cancer. Journal of Nuclear Medicine. 63(8): jnumed.121.263511. DOI: 10.2967/jnumed.121.263511.
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