In the current study, Coukos and his team identified two chemokines, CCL5 and CXCL9, that are consistently associated with CD8+ T cell infiltration of solid tumors. They show that CCL5 is ...

A subset of CD8+ T cells is increased in the blood and inflamed tissues of patients with a variety of autoimmune diseases and in COVID-19 patients with autoimmune-related complications.

In the largest study of its kind, researchers from The University of Texas MD Anderson Cancer Center identified three ...

Researchers at the VIB-KU Leuven Center for Cancer Biology have uncovered that "natural killer" cells (NK), a type of immune ...

Virtual memory CD8+ T cells (T VM) are a relatively recent discovery in humans. A new review discusses what is known about them from mouse models and their cellular equivalents in humans ...

In another they will try to discover how maturing CD8 T cells become either bloodborne cytotoxic CD8 cells or tissue-transiting, non-cytotoxic CD8 T cells. More information: Marcus Buggert et al.

Researchers have found that antigen-specific killer T cells (CD8+ T cells) rapidly expand in the lungs when primed by antigen-presenting lung-resident alveolar macrophages (AMs). This interaction ...

Study uncovers a pathogenic subset of memory T-cells that promote tissue inflammation and highlights a potential target for treating nasal polyps and other inflammatory airway diseases. Study ...

A variant form of LGL leukemia involves a specific T cell called CD8+. CD8+ T cells are T cells that carry the co-receptor CD8. A co-receptor is a surface protein that makes antigen receptors more ...