To realize an efficient hybridization of oligonucleotides, a DNA self-assembled monolayer (SAM) composed of branched probe DNA containing single- and double-stranded portions was prepared on a gold ...

Hepatitis B virus (HBV) infection remains a major global health concern, necessitating the development of sensitive and reliable diagnostic methods. In this study, we propose a novel approach to ...

Genomic and epigenomic patterns within DNA molecules are pivotal for a broad spectrum of in-vitro diagnostic applications, including companion diagnostics (Fridlyand et al, 2013; Van Neste et al, 2011 ...

Currently, several technologies have been developed for HCV RNA detection, such as branch DNA assay, real-time quantitative polymerase chain reaction coupled with reverse transcription (RT-qPCR), ...

EpiCypher, a leader in epigenomic technologies, has introduced two innovative DNA methylation sequencing assays - CUTANA® meCUT&RUN and Multiomic CUT&RUN - that offer scalable, high-resolution ...

The discovery that FANCM’s domains physically interact suggested they might functionally cooperate in migrating these branched DNA structures. To test this, we developed a novel real-time assay using ...

Not all medicines and/or indications presented in this report may be approved for use in all countries. Please note data included in this report are based on EU data and may vary depending on local ...

PD-L1 expression on circulating tumor cells and CTC clusters as a minimal cellular disease in breast cancer patients. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I. This ...

ctDNA-guided adjuvant chemotherapy escalation in stage III colon cancer: Primary analysis of the ctDNA-positive cohort from the randomized AGITG dynamic-III trial (intergroup study of AGITG and CCTG).

The Ho was highest in the Tongjiang goat at 0.2931, whereas the Chengdu grey goat had the lowest Ho at 0.2507. The He of six goat populations was remarkably similar (Supplementary Table S5).Conversely ...