Functional and connectivity changes in corticostriatal systems have been reported in the brains of patients with obsessive–compulsive disorder (OCD); however, the relationship between basal ...

A brain region commonly associated with OCD is the basal ganglia. The basal ganglia is a collection of structures underneath the cortex, the largest part of the brain. Like a secret agent ...

Basal ganglia dysfunction in OCD: subthalamic neuronal activity correlates with symptoms severity and predicts high-frequency stimulation efficacy. Translational psychiatry, 1(5), e5.

This corresponds to what specialists currently understand about the underlying mechanisms of diseases that affect the basal ganglia. Says Costa: "It is thought that in OCD, which is characterized ...

Their coordination with the basal ganglia sheds light on the genesis of OCD. Formally, there are two theories proposed to explain the interaction of basal ganglia and ACG/OFC.

These immune attacks may ultimately disrupt the cortical-basal ganglia circuit, leading to OCD symptoms. Swedo has found that severe tics characteristic of Tourette’s disorder can also appear ...

Previous studies with deep brain stimulation and people with OCD found a low-frequency brainwave appearing in the basal ganglia — an area of the brain involved in coordinating movement ...

There is also a sense that there are particular parts of the brain, which can't be turned off in OCD. There's a very deep part of the brain called the basal ganglia, which holds patterns for ...

“The basal ganglia are especially important for the internal generation of our actions, when there is no external stimulus,” he says. This is exactly what is happening in OCD. And researchers ...

Obsessive–compulsive disorder (OCD) is a common and debilitating disorder, which an estimated 2%–4% of individuals will develop before the age of 18 years.1 The pathogenesis is presumed to involve ...