An assay’s suitability for high throughput screening is measured using Z′ or RZ′ calculations. Z′ or RZ′ above 0.5 indicates that an assay is suitable for high throughput screening, meaning the fold ...

Immobilization of T4 bacteriophage onto the SPEs was achieved via EDC by formation of amide bonds between the protein coating of the phage and the electrochemically generated carboxylic groups at the ...

The U.K. Medicines and Healthcare products Regulatory Agency (MHRA) has issued its first official guidance on how to develop bacteriophages as licensed medicinal products. This covers personalized ...

The MTT assay, a widespread colorimetric biological technique, is used to test the viability of various cell types, such as fibroblasts (Scelza et al. 2012), odontoblasts (de Castilho et al. 2012), ...

We demonstrated a lateral flow immunoassay (LFA) for detection of viruses using fluorescently labeled M13 bacteriophage as reporters and single-reporter counting as the readout. AviTag-biotinylated ...

Tempus is presenting new data on xM for TRM at the 2025 American Society of Clinical Oncology (ASCO®) Annual Meeting, highlighting the assay’s potential to help clinicians monitor response and ...

The LAMP assay specifically targets the H5 hemagglutinin gene of the avian influenza virus. This assay offers important advantages over traditional diagnostic methods, Kamel noted. It detects the ...

Bacteriophage therapy, first applied in 1919 to be forgotten after the large-scale introduction of antibiotics in the 1940s, was rediscovered in the midst of the global antimicrobial resistance crisis ...

总之，phi027 bacteriophage在C. difficile的生理和毒力中扮演了关键角色。 通过去除prophage，研究人员揭示了其在孢子形成、adhesion和毒素产生中的重要作用。 这些结果为C. difficile的流行病学研究和治疗策略的开发提供了重要的科学依据。