For functional analysis of genomic DNA of higher eukaryotes, stable cloning of large genomic fragments is well established in bacterial artificial chromosomes (BACs) and in P1-based artificial ...

The DNA of mammalian cells can be damaged by various endogenous and exogenous insults, leading, if unrepaired, to genomic instability. Recently it has become apparent that bacterial pathogens can ...

Whether you had breakfast this morning or not, your pancreas is working quietly behind the scenes. This vital organ produces ...

Bacterial DNA may integrate into the human genome more readily in tumors than in normal human tissue, according to a new study. Researchers analyzed genomic sequencing data available from the ...

The Bacterial Genomic DNA Isolation Kit was used to isolate genomic DNA from 1 mL overnight culture (1 x 10 9 cells) of the Gram negative bacteria E. coli (Lanes 1 and 2), the lysozyme-resistant ...

Whereas CRISPR is best at making small, targeted modifications to a genome, bridge RNA gives genetic engineers a power they’ve never had before—to add, remove, invert, or rearrange large ...

Bacteria and their viruses have been locked in battle for eons, as viruses try to inject their DNA into the bacterial genome and bacteria devise cunning methods (e.g. CRISPR) to defend themselves.

Bacterial Defense: DdmD and DdmE proteins use guide DNA to identify and degrade plasmids in bacteria. Genome Editing Potential: The guide DNA used in this system may be more stable and cost-effective ...