Giant axonal neuropathy (GAN) is a rare autosomal recessive neurodegenerative disorder, characterised clinically by the development of chronic distal polyneuropathy during childhood, mental ...

Peripheral neuropathy is a common finding in patients with complex inherited neurological diseases and may be subclinical or a major component of the phenotype. This review aims to provide a clinical ...

The node of Ranvier and paranode have emerged as targets for immune-mediated pathology in GBS, CIDP and multifocal motor neuropathy (MMN).36 Gangliosides, glycosphingolipids containing sialic acid, ...

Charcot-Marie-Tooth neuropathy; CMT2; axonal CMT; genetic linkage; chromosome 12q; Charcot-Marie-Tooth (CMT) disease is a clinically and genetically heterogeneous group of disorders that involve the ...

Patients with small fiber neuropathy and cerebellar ataxia were more likely to have anti-gliadin antibodies when a lower test ...

INTRODUCTION. Multifocal motor neuropathy (MMN) is characterized clinically as an asymmetric progressive weakness predominantly in the upper limbs. 1, 2 Pure motor weakness must be present for more ...

For many individuals suffering from peripheral neuropathy, the frustrating cycle of numbness, tingling, and burning can feel like an endless battle—one that they’ve been told has no solution.… ...

Previous studies showed that multiple pathological mechanisms contributed to development of paclitaxel-induced neuropathy, involving metabolic dysregulation, covalent modification, organelle ...

Electrophysiological testing demonstrates an axonal pattern. Multifocal neuropathy is by no means specific to diabetic patients, underlining the need to exclude a superimposed cause of neuropathy ...

Diabetic neuropathy is the most common neuropathy in industrialized countries, and it is associated with a wide range of clinical manifestations. The vast majority of patients with clinical ...