R package with collection of functions created and/or curated to aid in the visualization and analysis of single-cell data using R.

The two companies have completed a successful proof-of-concept study which demonstrated the feasibility of using Cepheid's cartridge-based GeneXpert system for sample and library preparation in a ...

ATAC-seq在植物研究中具有巨大应用潜力 基于GEO、PubMed等已发表ATAC-seq研究物种统计，植物相关ATAC-seq研究占比不足10%，在植物 ...

3). Activity screening for these SNP harbouring enhancer elements was performed as in the marker gene assessment with ATAC-seq for open chromatin and ChIP-seq of H3K4me1 and H3K27ac signals. Contact ...

Design Two immunotherapy-resistant HCC models were generated by serial orthotopic implantation of HCC cells through anti-PD-L1-treated syngeneic, immunocompetent mice and interrogated by single-cell ...

随着测序技术的发展，性别决定机制不仅依赖遗传信息，也会受到表观遗传修饰的动态调控。 2. 通过文献案例介绍了整合表观组学（WGBS、ATAC-seq）和转录组学（RNA-seq）系统解析性腺分化过程中的动态调控网络的研究思路。 3. 派森诺表观调控领域六大核心产品和 ...

为探究结缕草在干旱时染色质可及性变化，研究人员开展了多组学研究。结果发现‘X4’品种耐旱性强，63 个高置信基因与干旱胁迫相关，还鉴定出 6 个调控干旱反应基序。该研究为结缕草改良育种奠定基础。

R package that automatically classifies the cells in the scRNA data by segregating non-malignant cells of tumor microenviroment from the malignant cells. It also infers the copy number profile of ...

We are currently applying multiple genomic, epigenetic, and proteomic techniques to address this question; these techniques include chromatin immunoprecipitation (ChIP), ChIP-Seq, RNA-Seq, RNA ...

School of Public Health, Food Safety and Health Research Center, Guangdong Provincial Key Laboratory of Tropical Disease Research, Southern Medical University, Guangzhou 510515, China ...

Integrated analysis of ChIP-seq, ATAC-seq and RNA-seq recognized that SIRT1 was the key gene affected by IDH1 deficiency. Thus, our current work provided novel insights for further clarifying ...