Mesenchymal chondroprogenitor cells differentiate into chondrocytes through cellular condensation processes, which are then surrounded by an abundant layer of extracellular matrix, including type II, ...

Conversely, articular cartilage also generates factors that impact lung diseases ... Interventions aimed at promoting chondrocyte growth, inhibiting apoptosis, and enhancing the production of ...

Articular cartilage can be damaged by a traumatic injury ... Osteochondral allograft surgery can also be performed as a salvage procedure for other failed cartilage repair surgeries. Cartilage ...

This content was created by our physicians and experts. Articular cartilage lines the ends the bones that form our joint surfaces and is composed of cells called chondrocytes, with a matrix or ...

Type I collagen in the dermis is a major component of the skin, though how this collagen is formed and modified as remained unclear. Here they show that keratinocytes contribute to dermal collagen ...

This study presents an important finding on the role of GATA4 in aging and OA-associated cartilage pathology. The evidence supporting the conclusions is compelling, with rigorous in vitro and in vivo ...

School of Nano-Tech and Nano Bionics, University of Science and Technology of China, Hefei 230026, Anhui, China CAS Key Laboratory of Nano-Bio Interface, Suzhou Institute of Nano-Tech and Nano-Bionics ...

Find more information on the Altmetric Attention Score and how the score is calculated. The extracellular matrix (ECM) is a critical non-cellular component of multicellular organisms containing a ...

The successful treatment of focal full-thickness articular defects of the knee ... cells of a committed pathway to develop hyaline-like cartilage. This hyaline-like cartilage more closely ...