These secrete large amounts of the cartilage extracellular matrix, which contains collagen and proteoglycans. Cartilage has limited repair capacity once damaged.

We first address the etiopathophysiology of OA and the mechanisms responsible for breakdown of the cartilage extracellular matrix. We then discuss the potential of MSCs for articular cartilage ...

Nanomechanical phenotype of chondroadherin-null articular cartilage. Matrix Biol ... Han. Molecular adhesion between cartilage extracellular matrix macromolecules. Biomacromolecules 2014. 15: 772-780.

Hyaline cartilage consists of round chondrocytes, which are cells that produce collagen, embedded within a dense extracellular matrix (ECM). This ECM acts as a physical scaffold ... is to provide an ...

Most cartilage relies on an external extracellular matrix for strength, but "lipocartilage," which is found in the ears, nose and throat of mammals, is uniquely packed with fat-filled cells called ...

Recent research has uncovered a pivotal role for hyaluronic acid (aka hyaluronan, HA), a glycosaminoglycan found in the ...