In December 2024, the National Comprehensive Cancer Network® (NCCN) added AUCATZYL (obecabtagene autoleucel) to its Clinical Practice Guidelines in Oncology (NCCN Guidelines®) for the treatment of ...

Expansion of CAR-T cells paralleled with the complete depletion of circulating B cells. B cell aplasia lasted for 119 days in patient 1, while patient 2 is still in B cell aplasia (day 60). Both ...

Patients with acute promyelocytic leukemia (APL) often present with potentially life-threatening hemorrhagic diathesis. The underlying pathomechanisms of APL-associated coagulopathy are complex.

The patient's 12-year-old sister also had aplasia cutis congenita (ACC) (with similar lesions on the right leg) and EB. The management was conservative, and the patient was maintained under ...

For seven decades, the pathophysiology of Good’s syndrome (GS) has remained a mystery, with few attempts to solve it. Initially described as an association between hypogammaglobulinemia and thymoma, ...