Ganglioside D3 (GD3) is overexpressed by perilesional epidermal cells, including melanocytes, which prompted us to generate GD3-reactive chimeric antigen receptor (CAR) Tregs to treat vitiligo. Mice ...

Furthermore, we demonstrated that dietary antigens are essential for a normal antigen-specific IgA response to Salmonella typhi serovar Typhimurium infection. These results provide new insights into ...

A personalized neoantigen cancer vaccine generated strong immune responses in renal cell carcinoma patients, leading to ...

A team of biomolecular engineers, pathologists, and internal medicine specialists at the University of Texas Medical Branch, ...

Patients with advanced kidney cancer who received an experimental vaccine after their tumors were removed were still ...

The Phase 1b/2a study will assess the safety of CNP-103 in adults (aged 18-35) and pediatrics (aged 12-17) who have Stage III or newly diagnosed (within the last 6 months) T1D as well as C-peptide ...

Chimeric antigen receptor-T (CAR-T) cell therapy, initially successful in hematologic malignancies, presents a promising avenue for treating solid tumors, including CRC. This review explores the ...

A new study by UC San Francisco found that prostate cancer cases are increasing in California, likely due to a change in ...

The Olympian told the BBC hearing he has motivated other men to get tested "helps me make sense of my situation".

Scientists have identified a key food allergen behind eosinophilic esophagitis, offering new hope for diagnosis and treatment ...