Bantam Pharmaceutical, a drug discovery and development company targeting selective modulation of mitochondrial dynamics in cancer, today announced solid tumor regression data from Bantam's lead ...

BriaPro is developing novel antibodies to B7-H3, a key cancer antigen and immune checkpoint Highly expressed on the cell surfaces of both tumor and immune cells, B7-H3 is a promising anti-cancer ...

编者按原发性胆汁性胆管炎（Primary Biliary Cholangitis, PBC）是一种免疫介导的慢性肝内胆汁淤积性疾病，主要特征为肝内小胆管损伤，逐渐发展为肝纤维化、肝硬化，具体发病机制尚不清楚。在血清学方面，90%以上的患者抗线粒体抗体 ...

Cholesterol is critical for mitochondrial membrane structure and function ... PCSK9 from protein lysates of H9c2 cardiomyocytes overexpressing PCSK9-V5 or the ER-bound mutant PCSK9 Q152H-V5 using the ...

That’s why you’ll see this article use terms like “support healthy aging” rather than “anti-aging ... EGCG may work by restoring mitochondrial function in cells and acting on pathways ...

2-Keto-3-ethoxybutyraldehyde bis(thiosemicarbazone) (KTS) has been shown to have marked carcinostatic and carcinolytic activity against several established rat tumors ...

Everything the brain does—from storing memories to interpreting sights to regulating emotions—requires energy, all produced by cellular organelles called mitochondria. However, surprisingly ...

For instance, mtDNA (or other extracellular mitochondrial components not measured in this study) could activate TLRs on immune or glial cells to release pro-inflammatory cytokines, such as IL-6 ...

Further investigation is needed to explore its potential as an ingredient in functional foods and anti-fatigue supplements ... such as AMPK, mitochondrial biogenesis, and FOXO3, to fully ...