The AHA has published a scientific statement regarding cardiovascular toxicity in patients with history of treatment for childhood cancer.

Developing a new regimen is urgently needed. This phase I study evaluated the maximum tolerated dose (MTD), safety, and efficacy of mitoxantrone hydrochloride liposome (Lipo-MIT) plus cyclophosphamide ...

Novel biomarkers, such as dysfunctional miRNAs (e.g., miRNA-34a), are closely linked to anthracycline-treated patients. Additionally, human induced pluripotent stem cell-derived cardiomyocytes ...

“These comorbidities have significant implications given data showing that anthracycline-treated survivors who de­velop hypertension and diabetes have a [greater than] 35-fold risk of developing ...

Department of General Surgery, Tianjin Union Medical Center, Tianjin 300122, P. R. China These authors contributed equally to this work.

This study provides valuable insights into the efficacy and safety of pyrotinib as an extended adjuvant therapy following trastuzumab-based treatment in patients with high-risk HER2-positive breast ...

The study by Ma et al. provides fundamental findings and compelling evidence that Pyrotinib after trastuzumab-based adjuvant therapy in patients with HER2-positive breast cancer (PERSIST): A ...

While several therapies are approved to treat relapsing forms of MS, only mitoxantrone is available for people with nonactive SPMS. Tiziana’s therapy works by blocking the CD3 receptor protein ...

米托蒽醌（mitoxantrone）对 UC 可能有免疫抑制治疗作用。此外，DR-JOBS 还发现了 NSAIDs 在不同自身免疫性疾病中的新用途。5. 药物验证：采用三种正交策略对 DR-JOBS 识别的药物进行验证，包括使用电子健康记录（EHR）数据检查药物对自身免疫性疾病患者炎症标志物 ...

The relationship between AL and anthracycline cardiotoxicity is unclear. In this large diverse cohort of individuals with cancer, we found that non‐Hispanic Black and Hispanic individuals had a higher ...

The study reported no cardiotoxicity with Berubicin, unlike other anthracyclines, and comparable overall and progression-free survival. Feel unsure about the market’s next move? Copy trade ...