ANCA相关性小血管炎性肾损害的治疗分为三个阶段：诱导缓解、维持缓解的治疗以及复发的治疗。诱导期通常维持3~6个月，必须持续至病情缓解为止，病情缓解后维持治疗时间一般持续24个月左右。目前，ANCA相关性小血管炎性肾损害仍无标准的治疗方案，糖皮质激素 ...

Patients with AAV are associated with an increased risk for MI, particularly during the first 3 months after diagnosis.

Antineutrophil cytoplasm antibody (ANCA)-associated vasculitis (AAV) is characterised by a small to medium-size vasculitis and the presence of ANCA. AAV includes microscopic polyangiitis (MPA), ...

The histopathologic features of eosinophilic angiocentric fibrosis overlap with IgG4-RD and AAV, making diagnosis difficult.

Patients with AAV who received avacopan vs standard glucocorticoid-based regimens had lower exposure-adjusted rates of AEs, infections, and neutropenia/lymphopenia.

A 34-year-old man was admitted to the hospital because of left ear pain with hearing loss and facial droop on the left side. Computed tomography showed a nasopharyngeal mass. A diagnosis was made.

Objective Treatment-refractory antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a life-threatening condition without evidence-based treatment options. One emerging treatment ...

Objective To compare acute treatment responses and long-term outcome in leucine-rich glioma-inactivated 1 (LGI1) antibody encephalitis. Methods Retrospective case series of 118 patients with LGI1 ...

Iluzanebart’s failure is another ding for a TREM2 space that has already seen a recent high-profile failure. Last November, Alector’s TREM2 antibody failed its own Phase II study for Alzheimer’s ...

Infection with the Omicron variant of SARS-CoV-2 has minimal impact on antineutrophil cytoplasmic antibody (ANCA) formation, which is central to the pathogenesis of ANCA-associated vasculitis (AAV), ...