Attempts to design small molecule therapies directed to this cytokine have not led to approved products yet. Here we report the discovery and development of a potent small molecule inhibitor of TNF ...

which has thus become one of the most important means we have for investigating molecular structure. There is, indeed, no experimental method that gives more detailed information on this subject.

This study investigates the potential clinical synergy between the PARP inhibitor niraparib (Zejula) and concomitant statins, exploring their combined effects on progression-free survival (PFS) in ...

A NUMBER of methods are available for the separation of the unbranched (amylose) and branched (amylopectin) components of starch. Of these methods, that of T. Schoch 1 has been generally useful ...

He graduated in 1964 from the University of Edinburgh with a degree in chemistry, which led to a research position studying the molecular structure of natural gums in specimens of acacia plants ...

These shifts highlight specific molecular mechanisms ... such as immune signaling and neuronal structure maintenance. These analyses uncovered significant losses in neurogenic potential and ...

You may have access to this article through your institution. Your institution does not have access to this content. Add or change your institution or let them know you’d like them to include access.

The structure of α-D-glucopyranose constituting the polysaccharides in rice has chirality and lacks inversion symmetry. In the starch crystalline domains, amylopectin chains have orderly structures ...

Shanghai Engineering Research Center of Molecular Therapeutics & New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, China ...

Molecular Cancer Research publishes articles featuring novel, basic cancer research discoveries that prioritize broad molecular and cellular processes. Areas of emphasis include cell cycle and ...

Capital structure is the mix of debt and equity that fund a company's operations. A judicious use of debt and equity is a key indicator of a strong balance sheet. A healthy capital structure that ...