Scientists have unlocked new details on important receptor proteins—promising targets for the creation of novel drugs for ...

Scientists have unlocked new details on important ‘receptor’ proteins –promising targets for the creation of novel drugs for ...

In many bacterial pathogens, the second messenger c‐di‐GMP stimulates the production of an exopolysaccharide (EPS) matrix to shield bacteria from assaults of the immune system. How c‐di‐GMP induces ...

Find more information on the Altmetric Attention Score and how the score is calculated. Ligand binding to membrane proteins may be significantly influenced by the interaction of ligands with the ...

For model benchmarking, Gcoupler was validated on GPCRs from the DUD-E dataset, alongside the information about the active ligands and their randomly selected number-matched decoys (35). Additionally, ...

† Department of Neuroscience and Pharmacology, Faculty of Health and Medical Sciences, The Panum Institute, University of Copenhagen, Blegdamsvej 3, Dk-2200 Copenhagen, Denmark ‡ Department of Physics ...

Contributed by J. Andrew McCammon, July 27, 2016 (sent for review June 24, 2016; reviewed by Richard J. Lewis and Jung-Hsin Lin) ...

Contributed by Russell A. DeBose-Boyd; received December 18, 2024; accepted April 11, 2025; reviewed by Peter Espenshade and Randolph Y. Hampton Mutations in the gene encoding UbiA prenyltransferase ...