资讯

Atomic-level mapping of receptor protein reveals potential drug targets for diabetes and ...
Scientists have unlocked new details on important receptor proteins—promising targets for the creation of novel drugs for ...
Queen's University Belfast1 天
New research discovery could advance drug treatments for diabetes and obesity
Scientists have unlocked new details on important ‘receptor’ proteins –promising targets for the creation of novel drugs for ...
C&EN2 天
Allosteric Modulation of Grb2 Recruitment to the Intrinsically Disordered Scaffold Protein ...
Results from a series of LAT constructs with combinatorial mutations of tyrosine residues reveal a previously unidentified allosteric mechanism in which the binding affinity of LAT:Grb2 depends on the ...
C&EN2 天
Defining the Structural Basis for Allosteric Product Release from E. coli Dihydrofolate ...
Department of Integrative Structural and Computational Biology and Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, ...
The EMBO Journal6 天
Allosteric activation of exopolysaccharide synthesis through cyclic di‐GMP‐stimulated ...
In many bacterial pathogens, the second messenger c‐di‐GMP stimulates the production of an exopolysaccharide (EPS) matrix to shield bacteria from assaults of the immune system. How c‐di‐GMP induces ...