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过敏性疾病与神经精神障碍的双向因果关联:孟德尔随机化研究
会轻微增加过敏性结膜炎(allergic conjunctivitis, AC)风险(OR=1.020)。 敏感性分析结果令人振奋:所有关联均未表现出显著异质性或水平多效性(horizontal pleiotropy)干扰。最终结论指出:AA和AD是抑郁症的独立危险因素;AA和AR显著提升BD发病风险;ASD对AU具有保护效应 ...
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