BMPER attenuated PI3K/AKT signaling and suppressed BMP4-driven smooth muscle activation in models of PAH. BMPER overexpression mitigated the vascular remodeling that characterizes pulmonary arterial ...

The following is a summary of “ER-α36 prevents high glucose-induced cellular senescence and apoptosis in renal tubular cell,” ...

Investigating tirzepatide's role in Alzheimer's reveals its potential to improve brain function and reduce inflammation, ...

NUCKS1 regulates the invasion and metastasis of CRC via the HDAC2/AKT signaling pathway 蛋白质组学筛选出643个差异蛋白，其中HDAC2与NUCKS1表达呈正相关。机制研究表明，NUCKS1过表达使HDAC2和磷酸化AKT(p-AKT Ser473 ...

Based on the results of experimental studies involving malignant gliomas that rely on paracrine or autocrine stimulation of receptors that trigger the PI3/Akt pathway, studies directed at ...

PI3K/AKT 信号通路参与调节细胞的糖代谢 ... 图. BZA-enhanced 5-FU-induced cell apoptosis is partly related to the Bad/Bcl-2 signaling pathway in colon cancer HT29 and SW480 cells ...

磷脂酰肌醇 3-激酶（PI3K）/蛋白激酶 B（AKT）/哺乳动物雷帕霉素靶蛋白（mTOR）通路是细胞内重要的信号传导通路之一，该通路的异常激活在多种疾病特别是恶性肿瘤中发挥着关键作用。近年来，靶向 PI3K/AKT/mTOR ...

Such a cobblestone tongue is a telltale sign of a rare genetic condition called Cowden syndrome. It's caused by inherited ...

Emerging evidence highlights the critical role of vitamin D3 in cellular aging and immune health, particularly through its potential to preserve leukocyte | Drug Discovery And Development ...

Hepatocellular carcinoma (HCC) is the most common primary liver cancer and a leading cause of cancer-related deaths worldwide ...

This valuable study presents a novel approach to enhance the therapeutic potential of mesenchymal stromal cells (MSCs) by genetically modifying their glycogen synthesis pathway, resulting in increased ...