From the Haemostasis, Thrombosis and Vascular Biology Unit (A.B., G.Y.H.L.), University Department of Medicine, City Hospital, Birmingham, UK, and Center for ...

This important study presents a compelling theoretical framework for understanding phase separation of membrane-bound proteins, with a focus on the organization of tight junction components. By ...

Leukocyte adhesion proceeds in a cascade-like fashion ... that does not require signalling through G-protein-coupled receptors and the signalling steps leading to integrin activation are beginning ...

† Key Laboratory of Bionic Engineering (Ministry of Education), Jilin University, Changchun 130022, P. R. China ‡ Key Laboratory of Automobile Materials (Ministry of Education) and College of ...

Summary: New research identifies a promising strategy for correcting dopamine imbalances in the brain using a drug that blocks kappa opioid receptors (KOR). In mouse models with a rare mutation that ...

2020). Currently, pharmaceutical developers are focusing on the downstream pathway of TGF-β to find new clues to solve the problem of fibrosis. Integrins are the main cell adhesion receptors for the ...

kDivision of Pathology and Data Analytics, Leeds Institute of Medical Research at St James's University, University of Leeds, Leeds, UK ...

Adenosine receptors can be targeted for the treatment of various inflammatory diseases. In asthma and chronic obstructive pulmonary disease, A 2A receptor agonists prevent inflammatory cell ...