Acyclovir (as sodium) 500mg/vial; lyophilized pwd for IV infusion after reconstitution and dilution; contains sodium 49mg/vial. Give by IV infusion over 1 hour. Mucocutaneous herpes simplex ...

Acyclovir gets converted to acyclovir triphosphate, which then inhibits replication of herpes viral DNA by competitively inhibiting viral DNA polymerase, incorporating into and terminating the ...

but the potential for exploiting viral enzymes to develop potent and specific antiviral drugs was clearly demonstrated. Acyclovir subsequently became a successful treatment for HSV-1 and HSV-2.