Background and aim: The present study was conducted to examine the effect of activin A on activation of rat pancreatic stellate cells (PSCs). Methods: PSCs were prepared from rat pancreas using ...

Activin A在NEC模型小鼠肠道组织中表达上调 ELISA和WB显示NEC组Activin A蛋白水平显著高于对照组，免疫组化证实其定位在肠上皮和炎症浸润区域。 Activin A加剧NEC病理进程 ...

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为解决B细胞急性淋巴细胞白血病(B-ALL)中枢神经系统(CNS)浸润机制不明的问题，意大利研究团队开发了三维(3D)离体脑切片模型，通过微注射人B-ALL细胞系NALM6，发现促白血病因子Activin A可加剧白血病细胞增殖并诱导脑组织死亡，同时重塑小胶质细胞和星形胶质细胞的抗炎表型。

The aim of this study was to characterize the response of the hypothalamic-pituitary-adrenal system in the first hours of ischemic stroke and to relate its extent to the occurrence of acute ...

The hypothalamus, pituitary, and adrenal glands are dynamic endocrine organs during fetal development.1-3 The adrenal glands, in particular, exhibit remarkable transformation in size, morphology, and ...

Mechanisms that underlie the pathophysiology of the triphasic pattern of postoperative diabetes insipidus. (1) The first phase of diabetes insipidus is initiated by a partial or complete pituitary ...

In this study, molecular docking and molecular dynamics (MD) simulations were conducted to investigate both the binding site and interactions of 61 inhibitors with activin-like kinase-5 (ALK5) ...

18. Gebel P. Pituitary apoplexy: review of literature with a report of an unusual case associated with diabetes insipidus. Mil Med 1962;127:753-760. 19. Yue H, Huaqiu Z, Yong L, et al .The observation ...