然而，在两种不同的神经病理性疼痛模型（EAE 和慢性压迫性损伤）中，TNFR2 激活后 CNP 的减轻依赖于性腺激素 Activin-A。 这表明性腺来源的因子通过一种共同机制影响 TNFR2 介导的疼痛缓解，且与性激素无关。

Inhibin/activin subunits are expressed in a variety of tissues, including ovary, testis, placenta, adrenal, kidney, brain and pituitary gland. Inhibin A and Activin A have been reported to ...

The pituitary is the target for and site of synthesis of several growth factors that modulate hormone production and regulate pituitary cell growth. [2] Some growth factors are critical for normal ...

Single-cell transcriptomics of human cholesteatoma identifies an activin A-producing osteoclastogenic fibroblast subset inducing bone destruction. Nature Communications , 2023; 14 (1) DOI: 10.1038 ...