The widely used analgesic-antipyretic drug acetaminophen (APAP) is known to cause serious liver necrosis at high doses in man and experimental animals. For studies of toxic processes, 1H NMR ...

NMR spectroscopy can distinguish each isomer due to the observable differences in the aromatic regions (δ H 6-8 ppm, δ C 110-170 ppm) that stem from the various substitution patterns.