Aging involves gradual functional decline across various biological systems, including impaired cellular mechanisms such as ...

This useful study partially succeeds in providing solid evidence in support of the therapeutic potential of the plant-derived compound eugenol for ameliorating symptoms associated with STZ-induced ...

Autophagy is a process by which cellular material is degraded by lysosomes or vacuoles and recycled. Several autophagy pathways operate within a cell, including macroautophagy, microautophagy and ...

Recent studies have identified that autophagy activation in oral epithelial cells suppresses cancer cell survival by inhibiting key pathways such as the mammalian target of rapamycin (mTOR) and ...

AMPK is linked to numerous anti-aging biological processes, including proteostasis, mitochondrial biogenesis, autophagy, mitohormesis, inflammation, and neurodegeneration. As a result, AMPK plays ...

AMPK is associated with many anti-aging-related cellular processes, such as proteostasis, mitochondrial biogenesis, autophagy, mitohormesis, inflammation, and neurodegeneration. Therefore ...

He, H.J., Cen, X.H., Liang, Y.J., Zhong, J.M., Deng, J.H. and Jiang, Y.J. (2025) Progress in the Regulation of Lipid Metabolism by the Orphan Nuclear Receptor Nur77. Journal of Biosciences and ...

AMPK会抑制mTOR，从而启动自噬。 此外，ATG家族基因（Autophagy-related genes）在自噬过程中也起到了关键的信号传导作用，许多自噬相关的遗传变异会 ...

Autophagy is a conserved multistep catabolic process that degrades unfolded proteins ... In mouse lungs, it mitigates cigarette smoke-induced emphysematous COPD pathologies through the AMPK pathway, ...

The provided evidence is solid with state-of-the-art genetic analysis of large human cohorts followed by a comprehensive analysis of a mouse SLC39A5 knockout mutant, establishing that SLC39A5 plays a ...

Department of Food Quality and Safety, College of Food Science and Engineering, Jilin University, Changchun, Jilin 130062, P. R. China Department of Food Quality and Safety, College of Food Science ...