No large RNA structure database exists that correlates sequence with 3D topology. Successful protein-centric methods like AlphaFold remain unavailable for RNA, creating a critical gap in ...

This is an RNA molecule generated in the lab that the team first presented in 2023. The researchers from the Institute of Organic Chemistry were able to determine the 3D structure of SAMURI using ...

Ebbe Andersen and colleagues had previously used the cryo-EM SPA method to study the 3D structure of RNA origami but the folding process remained elusive. IPET allowed the researchers to capture a ...

This deep learning-based method utilizes an RNA language model to accurately predict RNA 3D structures. This method addresses the challenges of RNA's intrinsic structural flexibility and the ...

The scientists used cryo-electron microscopy to decipher the three-dimensional (3D) structure of the RNA polymerase. They shock-froze the RNA polymerase in two different states, free and bound to ...

To understand how RNA functions, it is essential for scientists to know its 3D structure. “NuFold is the RNA equivalent of AlphaFold. AlphaFold is the computational protein structure prediction method ...

Hoping to gain more insights into their biological functions, the research team decided to analyze the 3D structures of the RNA molecules. They took their samples to SLAC, where they used ...